Pan-Seared Chicken with NAC-Infused Garlic Herb Butter

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

Juicy pan-seared chicken breasts enhanced with a garlic herb butter infused with N-Acetyl Cysteine (NAC) for a subtle savory boost. This american-inspired chicken ready in about 25 minutes pairs boneless skinless chicken breasts, unsalted butter, garlic cloves for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 350 calories and feeds 2, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 10 min Cook: 15 min Serves 2 American cuisine 350 cal/serving
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Ingredients

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Instructions

  1. Step 1: Pat dry 2 boneless skinless chicken breasts (6 oz each) and season evenly with 1 tsp salt and 1/2 tsp black pepper on both sides.
  2. Step 2: Heat 2 tbsp olive oil in a large skillet over medium-high heat until shimmering, about 2 minutes.
  3. Step 3: Add the chicken breasts and sear for 5 minutes on one side without moving, until golden brown edges form.
  4. Step 4: Flip the chicken and cook for an additional 4 minutes on the other side until cooked through and internal temperature reaches 165°F.
  5. Step 5: Lower heat to medium and add 4 tbsp unsalted butter, 3 minced garlic cloves, 1 tsp fresh thyme leaves, 1 tsp chopped fresh rosemary, and 200 mg NAC powder to the skillet.
  6. Step 6: Continuously spoon the melted butter mixture over the chicken for 2 minutes until the garlic is fragrant and butter slightly thickens, infusing the NAC flavor.
  7. Step 7: Remove chicken from skillet and let rest for 5 minutes before serving, spooning remaining butter and herbs over the top.

Frequently asked questions

How long does Pan-Seared Chicken with NAC-Infused Garlic Herb Butter take to make?

Total time is about 25 minutes (10 min prep + 15 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Pan-Seared Chicken with NAC-Infused Garlic Herb Butter?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep unsalted butter from drying out.

Can I substitute ingredients in Pan-Seared Chicken with NAC-Infused Garlic Herb Butter?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Pan-Seared Chicken with NAC-Infused Garlic Herb Butter for a different number of people?

The recipe is written for 2 servings. Multiply each ingredient by (your serving target / 2). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Pan-Seared Chicken with NAC-Infused Garlic Herb Butter?

American chicken like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.

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