Cheeseburger Lettuce Wraps with Spicy Mayo

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

A low-carb take on classic cheeseburgers using crisp lettuce leaves as wraps, topped with melted cheddar and a zesty homemade spicy mayo. This american-inspired keto (keto, low-carb) ready in about 20 minutes pairs 80% lean ground beef, cheddar cheese slices, large leaves romaine lettuce leaves for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 480 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 10 min Cook: 10 min Serves 4 American cuisine 480 cal/serving
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Ingredients

Instructions

  1. Step 1: In a medium bowl, combine 1 lb ground beef with 1 tsp salt and 1/2 tsp black pepper. Form into 4 equal patties about 3/4 inch thick.
  2. Step 2: Heat 1 tbsp olive oil in a large skillet over medium-high heat. Cook the patties for 4 minutes on one side until browned.
  3. Step 3: Flip the patties and place 4 cheddar cheese slices on top. Cook an additional 3-4 minutes until cheese melts and patties are cooked through.
  4. Step 4: In a small bowl, mix 1/4 cup mayonnaise, 1 tbsp Sriracha sauce, and 1 tsp yellow mustard until smooth.
  5. Step 5: To assemble, lay 8 large romaine lettuce leaves flat. Place a cheeseburger patty in each leaf, top with 1 tbsp diced pickles and 1 tbsp spicy mayo.
  6. Step 6: Fold the lettuce around the filling and serve immediately as a handheld wrap.

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Frequently asked questions

How long does Cheeseburger Lettuce Wraps with Spicy Mayo take to make?

Total time is about 20 minutes (10 min prep + 10 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Cheeseburger Lettuce Wraps with Spicy Mayo?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep 80% lean ground beef from drying out.

Can I substitute ingredients in Cheeseburger Lettuce Wraps with Spicy Mayo?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Cheeseburger Lettuce Wraps with Spicy Mayo for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

Is Cheeseburger Lettuce Wraps with Spicy Mayo keto?

Yes — this recipe is tagged keto, low-carb based on its ingredient list. Always cross-check labels for packaged ingredients (sauces, broths, condiments) since formulations vary by brand.

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