Pan-Seared Chicken with Honey-Balsamic Glaze and Roasted Brussels Sprouts

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

Juicy pan-seared chicken breast topped with a tangy honey-balsamic glaze, served alongside caramelized roasted Brussels sprouts. This general-inspired chicken ready in about 40 minutes pairs salt, black pepper, olive oil for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 450 calories and feeds 2, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 10 min Cook: 30 min Serves 2 450 cal/serving
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Ingredients

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Instructions

  1. Step 1: Preheat oven to 425°F. Toss 12 oz halved Brussels sprouts with 1 tbsp olive oil, 1/2 tsp salt, and 1/4 tsp black pepper. Spread on a baking sheet and roast for 20 minutes until caramelized and tender.
  2. Step 2: While Brussels roast, season 2 boneless skinless chicken breasts evenly with 1 tsp salt and 1/2 tsp black pepper.
  3. Step 3: Heat 1 tbsp olive oil in a large skillet over medium-high heat. Add the chicken breasts and cook for 5-6 minutes per side until golden brown and cooked through. Remove chicken and set aside.
  4. Step 4: In the same skillet, reduce heat to medium-low and add 2 minced garlic cloves, sautéing for 30 seconds until fragrant.
  5. Step 5: Stir in 1/4 cup balsamic vinegar and 2 tbsp honey, simmering gently for 3-4 minutes until the sauce thickens and coats the back of a spoon.
  6. Step 6: Return chicken to the skillet and spoon the honey-balsamic glaze over each piece, cooking for 1 more minute to warm.
  7. Step 7: Toss roasted Brussels sprouts with 1 tbsp butter until melted and glossy. Serve chicken topped with glaze alongside Brussels sprouts.

Frequently asked questions

How long does Pan-Seared Chicken with Honey-Balsamic Glaze and Roasted Brussels Sprouts take to make?

Total time is about 40 minutes (10 min prep + 30 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Pan-Seared Chicken with Honey-Balsamic Glaze and Roasted Brussels Sprouts?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep salt from drying out.

Can I substitute ingredients in Pan-Seared Chicken with Honey-Balsamic Glaze and Roasted Brussels Sprouts?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Pan-Seared Chicken with Honey-Balsamic Glaze and Roasted Brussels Sprouts for a different number of people?

The recipe is written for 2 servings. Multiply each ingredient by (your serving target / 2). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Pan-Seared Chicken with Honey-Balsamic Glaze and Roasted Brussels Sprouts?

General chicken like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.