Sheet Pan Sesame Pork & Veggie Medley

By , Test Kitchen Director · Reviewed by AislePrompt Editorial · ·

Tender pork tenderloin coated in a sweet-savory sesame glaze, roasted with colorful vegetables on one sheet pan. This asian-inspired sheet pan ready in about 55 minutes pairs soy sauce, sesame oil, honey for a weeknight-friendly dinner that comes together with one pan and minimal cleanup. Each serving lands at about 450 calories and feeds 4, so it slots cleanly into a weekly meal plan and pairs well with a quick salad or grain on the side. Tap "Plan a meal with the AI" below to drop this recipe into your week and send the ingredients straight to Instacart. Nutrition values are approximate, calculated from USDA FoodData Central (fdc.nal.usda.gov) — verify against ingredient labels for any health-driven dietary plan.

Prep: 20 min Cook: 35 min Serves 4 Asian cuisine 450 cal/serving
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Ingredients

Instructions

  1. Step 1: Preheat oven to 425°F. Whisk 2 tbsp soy sauce, 1 tbsp sesame oil, 1 tbsp honey, 1 tbsp rice vinegar, 1/2 tsp garlic powder, and 1/2 tsp ginger powder in bowl. Coat pork medallions with half the glaze, marinate 15 minutes.
  2. Step 2: Toss 1 medium zucchini (sliced), 1 red bell pepper (sliced), and 1 small red onion (wedges) with 2 tbsp olive oil, 1/4 tsp salt, and 1/4 tsp black pepper on sheet pan. Roast 10 minutes.
  3. Step 3: Push vegetables to sides of sheet pan, add marinated pork medallions to center. Roast 15-20 minutes until pork reaches 145°F and vegetables are tender-crisp.
  4. Step 4: Brush remaining glaze over pork and vegetables. Sprinkle with 1 tbsp sesame seeds and serve immediately.

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Frequently asked questions

How long does Sheet Pan Sesame Pork & Veggie Medley take to make?

Total time is about 55 minutes (20 min prep + 35 min cook). Most home cooks find this fits comfortably into a weeknight; double the batch on Sunday for two dinners.

How do I store leftover Sheet Pan Sesame Pork & Veggie Medley?

Cool to room temperature within 2 hours, then store in an airtight container in the fridge for up to 4 days. Reheat covered in a 350°F oven for 10-12 minutes, or microwave at 70% power in 60-second bursts to keep soy sauce from drying out.

Can I substitute ingredients in Sheet Pan Sesame Pork & Veggie Medley?

Yes — most ingredients in this recipe have flexible swaps. For oil, use any neutral high-smoke-point oil (avocado, grapeseed, refined coconut). For aromatics, dried herbs at ⅓ the volume of fresh work in a pinch. The full ingredient list is shoppable on Instacart so you can see substitutes in real time.

How do I scale Sheet Pan Sesame Pork & Veggie Medley for a different number of people?

The recipe is written for 4 servings. Multiply each ingredient by (your serving target / 4). Cook time stays roughly the same up to 2x; for 3-4x batches, switch from a skillet to a sheet pan or stockpot so the food isn't crowded — overcrowding steams instead of browns.

What goes well with Sheet Pan Sesame Pork & Veggie Medley?

Asian sheet pan like this pair well with a simple grain (rice, couscous, or crusty bread), a quick salad with acid (lemon vinaigrette, pickled onions), and a pan sauce or yogurt-based dip. Tap "Plan a meal with the AI" to get specific side suggestions.

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